Food Industry News

Found cause of the excessive appetite

Neuroscientists from McGill University have discovered a group of nerve cells, which play a crucial role in the regulation of appetite and a tendency to obesity. NG2-glial cells proved to be responsible for the sense of satiety, and violation of the anticancer activity upon treatment enhances appetite.

The results are published in the journal Cell Metabolism.

About two decades ago, scientists discovered that the appetite is controlled by hormone leptin, which is produced by fat cells. It is delivered by the flow of blood into the brain, where it signals to certain centers of the latter that we are full and can no longer eat. Although leptin receptors have been found in the hypothalamus, it remains unknown how leptin affects food intake and weight.

In the new study, the researchers were able to answer this question. They drew attention to the cells in the median eminence of the hypothalamus, which are divided for most of life. The researchers used a special drug that contributes to the death of NG2-glial cells. It was found that without these experimental mice brain neurons can no longer receive signals from fat cells.

Three days after the start of the drug administration, some animals began to eat much more in large quantities than the control group of mice that did not receive the glial cell inhibitor. For 30 days their weight doubled: from 25 to 50 grams. Interestingly, other NG2-glial cells that were outside the midline elevation were not affected.

Scientists believe that there are hidden answer to the question why patients with brain cancer strangely tend to gain weight. Irradiation typically leads to suppression of glial cell division that leads to uncontrolled appetite. New techniques are directed at maintaining a population of neurons in the hypothalamus may help in the treatment of obesity.

See also ... 14/05/2012 Strong appetite warns of danger 14/10/2013 Scientists have found nerve cells to suppress appetite 12/07/2012 The influence of the stomach on the brain is stronger than we think 18/09/2012 The hormone of appetite causes alcoholism 23/08/2012 Ice cream on an innovative ingredient will help to fight obesity22 / 05/2013 Obesity changes the biochemistry of the brain 13/10/2014 Scientists explain the attraction of flies and humans to beer14 / 07/2014 Human biological clock associated with food29 / 09/2014 In curry discovered a cure for Alzheimer's 27 Cafes and restaurants in the Czech Republic offer heady jelly02 / 2014/28 Ros Sveta refers to food quite utilitarian11 / 2012/12 It will be possible to immediately identify food allergies03 / 2014/20 03 of the best breakfasts in the world2013 / 50/25 Fighting obesity in India is planned using food color coding11 / 2013/26 Schoolgirls suggested how to overcome the world hunger

Add a comment

Your email address will not be published. Required fields are marked *

This site uses Akismet to combat spam. Find out how your comment data is processed.